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Lyrica approved for Neuropathic Pain
  1. #1
    medik8 is offline Member
    Join Date
    Mar 2004

    Default Lyrica approved for Neuropathic Pain

    Lyrica (pregabalin) Capsules
    Approved: December 31, 2004 Company: Pfizer Inc.
    Treatment for: Neuropathic Pain
    Lyrica is a 3-substituted analogue of gamma-amino butyric acid (GABA) and a compound related to gabapentin (Neurontin). Lyrica is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy (DPN) and postherpetic neuralgia (PHN). more...

    More information on New Drugs

  2. #2
    rusty is offline Junior Member
    Join Date
    Sep 2004


    Lyrica Relieves Diabetes Pain
    Fri Jan 7, 2005 04:41 PM ET

    NEW YORK (Reuters Health) - A new drug, Lyrica (pregabalin) is a well-tolerated, effective treatment for pain in the extremities often experienced by people with diabetes, according to a recent report. In addition to reducing the pain, the drug seems to improve sleep.
    The findings, which appear in the medical journal Neurology, are based on a study sponsored by Pfizer, which markets Lyrica. Just last week, the FDA approved the drug specifically for painful diabetic neuropathy.

    The study involved 338 patients with diabetes-related pain who were randomly given Lyrica, at one of three doses, or inactive "placebo" for five weeks.

    The intermediate and highest doses of Lyrica, but not the lowest dose, were better than placebo at improving pain, Dr. Harold Lesser, from the University of Rochester School of Medicine & Dentistry in New York, and colleagues note. These doses were also tied to significant improvements in sleep and quality of life.

    People who were given Lyrica were also more likely to have a treatment response, meaning that they had a 50 percent or greater improvement in their pain. The two higher doses of Lyrica had responder rates of around 47 percent, whereas the rate with placebo was just 18 percent.

    The improvements in pain and sleep were noted within 1 week of treatment with Lyrica and continued throughout the study, the investigators point out.

    Treatment with Lyrica was well tolerated and side effects were generally mild, most commonly dizziness and sleepiness, the report indicates.

    The results suggest that Lyrica has the potential to become a first-line treatment for diabetes pain, Lesser's team notes.

    SOURCE: Neurology, December 15, 2004.

  3. #3
    Myki is offline Junior Member
    Join Date
    Dec 2004


    any follow ups on this? At present am on neurontin for neuropathy of all four extremities. It was ordered not so much for the pain but the involuntary jumping of my arms and legs but doesnt help much with the pain. would be interested in knowing.

  4. #4
    specialksmama is offline New Member
    Join Date
    Jun 2014


    My dr gave me Lyrica 75mg to help me sleep and they help, but as far as helping my chronic pain it doesn't help at all.

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