Results 1 to 3 of 3
Drug interaction between Pioglitazone and Glimepiride
  1. #1
    pmusmade is offline New Member
    Join Date
    Jan 2009
    Posts
    1

    Default Drug interaction between Pioglitazone and Glimepiride

    Dear All
    I want to Know , is there any Pharmacokinetic or CYP P450 drug interaction between Pioglitazone and Glimepiride which is present in fixed dose combination product.
    It will be good if any reference if available.

    Thanking you in advanced
    PRASHANT

  2. #2
    Join Date
    Feb 2009
    Location
    MO
    Posts
    110

    Default

    Pioglitazone is metabolized by CYP 450 3A4 and 2C8, Glimepiride by CYP 450 2C9 so no, they are different cytochrome P450 enzymes. I do not believe there is a pharmacokinetic interaction either, but don't have REALLY solid evidence I can give you.

    http://www.drugbank.ca/drugs/DB00222
    http://www.drugbank.ca/drugs/DB01132
    ---I answer questions to the best of my ability, but with always limited knowledge of the patient's situation and no ability to see your chart or full medical history my advice is limited and should also be confirmed with your own doctor/pharmacist/etc. Also, I do not promote following my advice without proper approval from your doctor either--

    Dr. B

  3. #3
    Robert_325 is offline Retired
    Join Date
    Jul 2007
    Location
    Texas
    Posts
    16,677

    Default

    Quote Originally Posted by pmusmade View Post
    Dear All
    I want to Know , is there any Pharmacokinetic or CYP P450 drug interaction between Pioglitazone and Glimepiride which is present in fixed dose combination product.
    It will be good if any reference if available.

    Thanking you in advanced
    PRASHANT




    There are no known interactions between these medications I am aware of. You can check them on the "drug interactions checker" at the top of this page where indicated just below the search box. I would read up on your medications so you're more informed for your own benefit. If you do a search here on the individual medications you have the option of basic information as well as detailed information designed for professionals as well as the consumer. Enter the medications in the search box and click the drug search button.

    I always suggest that members (especially those with multiple medications or medications they know little about) maintain an ongoing list of their medications in the Med Notes section of this web site. It's a great way to keep an ongoing record of our medications and all information we need to be kept informed about.

    You can maintain info on several people simultaneously so it's simple to track our children's meds, our parents meds, etc. There are lots of cool benefits available on this web site for our members if you check it out. I used it for years before I ever posted on the forum. God bless.
    I am not a dr. My statements are based on years of experience and related education. Consult with the professional of your choice regarding matters of concern.

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22